NRP 9th Ed · Lesson 7 · Medications

Neonatal Epinephrine Dose

Enter a weight and read the volume to draw. Epinephrine 1:10,000 (0.1 mg/mL), the only concentration NRP uses in the delivery room.

Birth weight

Volume to draw

0.60mL

Dose: 0.02 mg/kg
Total: 0.060 mg
Draw in: 1 mL syringe

1 mL barrel Graduations every 0.05 mL

Then flush with 3 mL of 0.9% normal saline, given rapidly.

Every dose at this weight

scale 0 – 3.00 mL

When to give it

Indication: HR < 60 bpm after at least 30 s of adequate PPV and chest compressions
Concentration: 1:10,000 = 0.1 mg/mL epinephrine HCl
Preferred access: Umbilical venous catheter, or intraosseous
Repeat IV / IO: Every 3–5 minutes while HR stays under 60 bpm
Repeat ETT: One dose only, then switch to IV / IO once access is in
After each IV / IO dose: Flush with 3 mL of 0.9% normal saline, rapidly

Clinical decision support only. This calculator implements epinephrine dosing from the NRP 9th Edition (American Academy of Pediatrics / American Heart Association). Verify every dose against your institution's protocol and the NRP Provider Textbook. PediaSuite is not affiliated with the AAP or AHA.

Reviewed by C. A. Leyva, MD, neonatologist · Last reviewed September 2026

References

American Academy of Pediatrics, American Heart Association. Textbook of Neonatal Resuscitation. 9th ed. Itasca, IL: American Academy of Pediatrics; 2025. Lesson 7: Medications.
Lee HC, Strand ML, Finan E, et al. Part 5: Neonatal Resuscitation: 2025 American Heart Association and American Academy of Pediatrics Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation. 2025;152(16 Suppl 2):S385–S423. doi:10.1161/CIR.0000000000001367

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