Patient data
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Bilirubin measurement
Neurotoxicity risk factors (AAP 2022)
AAP 2022: Any of the above factors defines elevated neurotoxic risk, lowering the clinical thresholds for phototherapy and exchange transfusion (dashed line on graph). Prematurity is incorporated into separate curves by gestational week.
Recommendation & interpretation
AAP 2022 treatment curve
Clinical decision support only. This tool implements the 2022 AAP Clinical Practice Guideline on hyperbilirubinemia (Pediatrics 2022;150:e2022058859). It does not replace clinical judgment. Always confirm management with your institutional protocol and a qualified physician. PediaSuite is not affiliated with the AAP or AHA.
Reviewed by C. A. Leyva, MD, neonatologist · Last reviewed September 2026
References
- Kemper AR, Newman TB, Slaughter JL, et al. Clinical Practice Guideline Revision: Management of Hyperbilirubinemia in the Newborn Infant 35 or More Weeks of Gestation. Pediatrics. 2022;150(3):e2022058859. doi:10.1542/peds.2022-058859
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