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NICU · Respiratory

Neonatal Surfactant Dose

Weight-based dose in mg and mL for Survanta, Curosurf, and Calfactant — the three FDA-approved natural surfactants used in US NICUs.

Birth weight

Initial dose volume

—mL
Dose
—
In mg
—
Concentration—
Repeat dose—
Repeat volume—
Max doses—
Administration—

Initial dose volume, all three, at this weight

—

Clinical decision support only. Dosing based on FDA prescribing information and AAP guidelines. Verify with pharmacy and institutional protocol. Administer only by trained NICU personnel with intubation equipment available. PediaSuite is not affiliated with any manufacturer or institution.

Reviewed by C. A. Leyva, MD, neonatologist · Last reviewed September 2026

References

  1. Polin RA, Carlo WA; Committee on Fetus and Newborn. Surfactant replacement therapy for preterm and term neonates with respiratory distress. Pediatrics. 2014;133(1):156–163. doi:10.1542/peds.2013-3443
  2. U.S. prescribing information (DailyMed): Survanta (beractant), Curosurf (poractant alfa), Infasurf (calfactant).
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